产品名称：Active Human Recombinant Tau (K18), P301L mutant Protein Pre-formed Fibrils
别名：Active tau PFFs, active tau protein preformed fibrils, active tau aggregates, microtubule-associated protein tau, MAPT, MAP, microtubule-associated protein, Paired Helical Filament-Tau, Phf-Tau, Neurofibrillary Tangle Protein, G Protein Beta1/Gamma2 Subunit-Interacting Factor 1, Isoform 4, tubulin-associated unit
TEM of recombinant Tau (K18), P301L mutant preformed fibrils (PFFs) at 150kx magnification. HV=80kV. Fibrils were sonicated and stained with uranyl acetate.
TEM of recombinant Tau (K18), P301L mutant preformed fibrils (PFFs) at 30kx magnification. HV=80kV. Fibrils were sonicated and stained with uranyl acetate.
Thioflavin T is a fluorescent dye that binds to beta sheet-rich structures, such as those in tau fibrils. Upon binding, the emission spectrum of the dye experiences a red-shift and increased fluorescence intensity. Thioflavin T emission curves show increased fluorescence (correlated to tau aggregation) over time in tau preformed fibrils (SPR-330). Tau preformed fibrils (SPR-330) seed the formation of new tau fibrils when combined with tau monomers (SPR-327). Thioflavin T ex = 450 nm, em = 485 nm.
SDS-PAGE of ~15 kDa Active Human Tau Protein K18 P301L Preformed Fibrils (SPR-330). Lane 1: MW Ladder. Lane 2: Tau Protein Preformed Fibrils (SPR-330).